ABSTRACT
<p><b>OBJECTIVE</b>To examine the urinary level of tissue factor (uTF) and its procoagulant activity (PCA) in patients with diabetes mellitus, and explore the relationship between uTF and renal damage in diabetes mellitus.</p><p><b>METHODS</b>Eighty-six patients with type 2 diabetes mellitus were divided into 3 groups according to urine albumin excretion (UACR), namely normal albuminuria group, microalbuminuria group and macroalbuminuria group. The levels of uTF, PCA, blood urea nitrogen (BUN), serum creatinine (CRE), serum cystatin C (CYSC), glycohemoglobin A1c (HbA1c), and high-sensitivity C-reactive protein (hs-CRP) were measured in all the patients and 21 healthy controls.</p><p><b>RESULTS</b>Compared with normal control, the diabetic patients showed significantly increased levels of uTF and PCA. The urinary TF-PCA was positively correlated to BUN, CYSC, CRE, UACR, fasting glucose and hs-CRP, but not to uTF; only hs-CRP, UACR were positively correlated to uTF.</p><p><b>CONCLUSION</b>uTF is probably implicated in the development and progression of diabetic nephropathy.</p>
Subject(s)
Adult , Female , Humans , Male , Middle Aged , Albuminuria , Urine , Blood Coagulation , Case-Control Studies , Creatinine , Urine , Diabetes Mellitus, Type 2 , Urine , Thromboplastin , UrineABSTRACT
<p><b>OBJECTIVE</b>To investigate the value of Tei index and the sensitivity of left versus right ventricular Tei index in evaluating the fetal cardiac function in pregnancy-induced hypertension syndrome in the third trimester.</p><p><b>METHODS</b>Fetal echocardiograms were performed in 30 women with pregnancy-induced hypertension (PIH) syndrome and 55 with normal pregnancy of the third trimester. Tei index was obtained by calculating the ratio of the isovolumic time (isovolumic contraction and relaxation time) to the ejection time of the left and right ventricle. Comparisons of the Tei index were made between the PIH group and control group, and also between the left and right ventricles in each group.</p><p><b>RESULTS</b>Significant difference was found in the left and right ventricular Tei index between PIH group and control group. No difference was noted between the left and right ventricular Tei index in the PIH group.</p><p><b>CONCLUSIONS</b>Tei index is a useful indicator in evaluating fetal global cardiac function, for which purpose the left ventricular Tei index can be as sensitive as the right ventricular Tei index.</p>
Subject(s)
Female , Humans , Pregnancy , Case-Control Studies , Fetal Heart , Diagnostic Imaging , Hypertension, Pregnancy-Induced , Pregnancy Trimester, Third , Sensitivity and Specificity , Ultrasonography, Prenatal , Ventricular Function, Left , Physiology , Ventricular Function, Right , PhysiologyABSTRACT
<p><b>OBJECTIVES</b>To evaluate the diagnostic value of color Doppler ultrasonography for epididymitis.</p><p><b>METHODS</b>High frequency color Doppler ultrasonography was performed in 42 patients with epididymitis and 21 health volunteers.</p><p><b>RESULTS</b>Compared with control group, epididymis enlarged significantly all in head, body and tail in 92% of patients with epididymitis. Bilateral epididymitis occurred in 73% of patients. Color Doppler flow imaging (CDFI), in patient group, showed the markedly increased flow signals bright in bundle in epididymis. Mild hydroccele of testis and orchitis were companied in most patients(93%). Orchitis was often complicated in the patients with long history.</p><p><b>CONCLUSIONS</b>High frequency color Doppler ultrasonography can be a preferred exam method and has diagnostic value for epididymitis.</p>
Subject(s)
Adolescent , Adult , Humans , Male , Middle Aged , Epididymitis , Diagnosis , Ultrasonography, Doppler, Color , MethodsABSTRACT
No abstract available.